Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 20/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 16/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14789797 | 1.00 | CYP11B2 (0.47) | CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL21535290 | 0.84 | CYP11B1 (0.41) | CYP11B2CYP11B1 | |
| SCHEMBL31259931 | 0.82 | CYP11B1 (0.44) | CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL14778968 | 0.82 | CYP11B1 (0.47) | CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL14778670 | 0.82 | CYP11B1 (0.44) | CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL14780274 | 0.82 | CYP11B1 (0.44) | CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL14789761 | 0.82 | CYP11B1 (0.60) | CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL14789952 | 0.78 | CYP11B1 (0.47) | CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL31259972 | 0.78 | CYP11B1 (0.47) | CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL777530 | 0.76 | ACVRL1 (0.57) | CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653618-B1 | NEW DIHYDROQUINOLINE-2-ONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2025-01-08 | — | — | EP | claimed |
| EP-3653618-B1 | NEW DIHYDROQUINOLINE-2-ONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2025-01-08 | — | — | EP | disclosed |