Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 12/20 | 0.58 |
| ▸ | CYP11B1 | P15538 | 10/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.51 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | WNT1 | P04628 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14789896 | 1.00 | CYP11B2 (0.58) | CYP11B2CYP11B1CYP1A2CYP2C9TBXAS1 | |
| SCHEMBL31260100 | 0.88 | CYP11B2 (0.60) | CYP11B2CYP11B1CYP1A2CYP19A1SCN2A | |
| SCHEMBL14792958 | 0.88 | CYP11B2 (0.60) | CYP11B2CYP11B1CYP1A2CYP19A1SCN2A | |
| SCHEMBL31259976 | 0.83 | CYP11B2 (0.50) | CYP11B2CYP11B1CYP1A2CYP2C9TBXAS1 | |
| SCHEMBL14779034 | 0.83 | CYP11B2 (0.50) | CYP11B2CYP11B1CYP1A2CYP2C9TBXAS1 | |
| SCHEMBL14789877 | 0.81 | CYP11B2 (0.65) | CYP11B2CYP11B1CYP1A2CYP19A1 | |
| SCHEMBL31259957 | 0.81 | CYP11B2 (0.65) | CYP11B2CYP11B1CYP1A2CYP19A1 | |
| SCHEMBL14789987 | 0.78 | CYP11B2 (0.62) | CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL31260002 | 0.78 | CYP11B2 (0.62) | CYP11B2CYP11B1CYP19A1 | |
| SCHEMBL21518692 | 0.76 | CYP11B1 (0.62) | CYP11B2CYP11B1CYP1A2CYP2C9TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653618-B1 | NEW DIHYDROQUINOLINE-2-ONE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2025-01-08 | — | — | EP | disclosed |