Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 17/20 | 0.46 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31264664 | 0.88 | EIF2AK3 (0.50) | EIF2AK3EIF2AK4RIPK1METAXL | |
| SCHEMBL31264760 | 0.88 | EIF2AK3 (0.50) | EIF2AK3EIF2AK4RIPK1METAXL | |
| SCHEMBL31264739 | 0.87 | EIF2AK3 (0.49) | EIF2AK3EIF2AK4RIPK1METAXL | |
| SCHEMBL31264734 | 0.84 | EIF2AK3 (0.47) | EIF2AK3EIF2AK4RIPK1METAXL | |
| SCHEMBL31264636 | 0.83 | FGFR1 (0.40) | — | |
| SCHEMBL20351783 | 0.72 | RIPK2 (0.61) | EIF2AK3EIF2AK4METAXL | |
| SCHEMBL31264749 | 0.70 | EIF2AK3 (0.47) | EIF2AK3RIPK1METAXL | |
| SCHEMBL25285654 | 0.70 | NEK7 (0.56) | EIF2AK3METAXL | |
| SCHEMBL28633632 | 0.70 | EIF2AK3 (0.51) | EIF2AK3 | |
| SCHEMBL31264649 | 0.70 | FGFR1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4722216-A1 | PYRROLOPYRIMIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | Kangbaida (Sichuan) Biotechnology Co., Ltd. (CN) | 2026-04-08 | — | — | EP | disclosed |
| CN-119894900-A | Pyrrolo pyrimidine derivative and application thereof in medicine | 康百达（四川）生物医药科技有限公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024251147-A1 | PYRROLOPYRIMIDINE DERIVATIVE AND USE THEREOF IN MEDICINE | 康百达（四川）生物医药科技有限公司 | 2024-12-12 | — | — | WO | disclosed |