Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASGR1 | P07306 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3129270 | 0.86 | ALDH1A1 (0.31) | — | |
| SCHEMBL3096236 | 0.78 | GAA (0.30) | — | |
| SCHEMBL6760751 | 0.74 | NPC1 (0.31) | SMN1; SMN2 | |
| SCHEMBL1470454 | 0.72 | — | — | |
| SCHEMBL12986611 | 0.72 | EPHX1 (0.31) | — | |
| SCHEMBL617542 | 0.69 | — | — | |
| SCHEMBL615881 | 0.66 | PDK1 (0.32) | — | |
| SCHEMBL13885605 | 0.65 | — | — | |
| SCHEMBL9336567 | 0.64 | — | — | |
| SCHEMBL13918235 | 0.64 | SMN1; SMN2 (0.31) | TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2054427-B1 | AVERMECTIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-07-14 | — | — | EP | disclosed |
| EP-2054427-A2 | AVERMECTIN DERIVATIVES | Bayer CropScience AG (DE) | 2009-05-06 | — | — | EP | disclosed |
| WO-2008019784-A2 | AVERMECTIN DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-02-21 | — | — | WO | disclosed |