Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 6/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3128370 | 0.78 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3HTR2AHTR2C | |
| SCHEMBL3124123 | 0.76 | IDO1 (0.52) | SLC6A4SLC6A2SLC6A3HTR2AHTR2C | |
| SCHEMBL19921471 | 0.73 | SLC6A2 (0.57) | TACR1SLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL3117949 | 0.72 | CARM1 (0.56) | TACR1SLC6A4SLC6A2SLC6A3HTR2A | |
| Hydrochloric Acid SCHEMBL1476112 | 0.72 | SLC6A2 (0.56) | TACR1SLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL3131468 | 0.71 | SLC6A2 (0.47) | SLC6A4SLC6A2SLC6A3HTR2AHTR2C | |
| SCHEMBL31071548 | 0.69 | SLC6A4 (0.60) | TACR1SLC6A4HTR2CHTR2BNAAA | |
| SCHEMBL30700754 | 0.68 | SLC6A4 (0.46) | TACR1SLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL102306 | 0.68 | CARM1 (0.58) | TACR1SLC6A4SLC6A2SLC6A3HTR2A | |
| SCHEMBL22283732 | 0.68 | IDO1 (0.56) | SLC6A4SLC6A2SLC6A3NAAAHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022055-A2 | INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | AMGEN INC. (US) | 2010-02-25 | — | — | WO | disclosed |