Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 15/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 15/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3131473 | 0.87 | CARM1 (0.44) | CARM1PRMT6DRD4DRD3TMEM97 | |
| SCHEMBL3122974 | 0.79 | SLC6A4 (0.55) | SLC6A2SLC6A4SLC6A3HTR2CHTR2A | |
| SCHEMBL3117949 | 0.77 | CARM1 (0.56) | SLC6A2SLC6A4SLC6A3HTR2CHTR2A | |
| SCHEMBL3124811 | 0.76 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3HTR2CHTR2A | |
| SCHEMBL2302468 | 0.74 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3HTR2CHTR2A | |
| SCHEMBL3122265 | 0.74 | KIF11 (0.39) | SLC6A2SLC6A4SLC6A3HTR2CHTR2A | |
| SCHEMBL102306 | 0.72 | CARM1 (0.58) | SLC6A2SLC6A4SLC6A3HTR2CHTR2A | |
| SCHEMBL3126567 | 0.71 | TACR1 (0.39) | SLC6A2SLC6A4SLC6A3HTR2CHTR2A | |
| SCHEMBL15000820 | 0.71 | SLC6A2 (0.43) | SLC6A2SLC6A4SLC6A3HTR2CHTR2A | |
| SCHEMBL19921515 | 0.70 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3HTR2CHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022055-A2 | INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | AMGEN INC. (US) | 2010-02-25 | — | — | WO | disclosed |