Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PLAU | P00749 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | PDE5A | O76074 | 2/20 | 0.46 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16504846 | 0.83 | KDM4E (0.53) | KDM4EMEN1KMT2AELANESMN1; SMN2 | |
| SCHEMBL28342069 | 0.81 | KDM4E (0.54) | KDM4EMEN1KMT2AF2PLAU | |
| SCHEMBL31716020 | 0.81 | ALDH1A1 (0.55) | KDM4EMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL28293697 | 0.81 | ADORA3 (0.61) | KDM4EMEN1KMT2AF2PLAU | |
| SCHEMBL16505669 | 0.79 | PDE3B (0.46) | KDM4EALDH1A1HPGD | |
| SCHEMBL8569908 | 0.78 | KDM4E (0.55) | KDM4EMEN1KMT2AF2PLAU | |
| SCHEMBL30641227 | 0.78 | KDM4E (0.55) | KDM4EMEN1KMT2AF2PLAU | |
| SCHEMBL26674806 | 0.78 | KDM4E (0.55) | KDM4EMEN1KMT2AF2PLAU | |
| SCHEMBL30017448 | 0.78 | ALDH1A1 (0.49) | KDM4EMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL27858013 | 0.78 | ABCG2 (0.73) | KDM4EMEN1KMT2ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4724430-A1 | CONDENSED AZINES AS INHIBITORS OF CYCLIC ADP RIBOSE HYDROLASE | Flagship Pioneering Innovations VI, LLC (US) | 2026-04-15 | — | — | EP | disclosed |
| WO-2024254396-A1 | CONDENSED AZINES AS INHIBITORS OF CYCLIC ADP RIBOSE HYDROLASE | FLAGSHIP PIONEERING INNOVATIONS, VI, LLC (US) | 2024-12-12 | — | — | WO | disclosed |