Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | STK3 | Q13188 | 2/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | PLK4 | O00444 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26604369 | 1.00 | LMNA (0.39) | LMNAKDM4ESMN1; SMN2MAPTHTT | |
| SCHEMBL26604519 | 0.91 | LMNA (0.36) | LMNAKDM4ESMN1; SMN2MAPTHTT | |
| SCHEMBL30662847 | 0.91 | LMNA (0.36) | LMNAKDM4ESMN1; SMN2MAPTHTT | |
| SCHEMBL26604498 | 0.84 | LMNA (0.34) | LMNAKDM4ESMN1; SMN2MAPTHTT | |
| SCHEMBL30662894 | 0.84 | LMNA (0.34) | LMNAKDM4ESMN1; SMN2MAPTHTT | |
| SCHEMBL31261879 | 0.82 | MEN1 (0.33) | KDM4ESMN1; SMN2MAPTHTTKMT2A | |
| SCHEMBL30662898 | 0.81 | CSF1R (0.32) | LMNAKDM4ESMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL26604545 | 0.81 | CSF1R (0.32) | LMNAKDM4ESMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL29223482 | 0.74 | ALDH1A1 (0.46) | SMN1; SMN2MAPTHTTALDH1A1 | |
| SCHEMBL31276667 | 0.74 | KDM4E (0.34) | KDM4ESMN1; SMN2MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119095849-A | Macrocyclic heterocycles and uses thereof | 金橘生物科技公司 | 2024-12-06 | — | — | CN | disclosed |