SCHEMBL31268802

SCHEMBL31268802

CC1(Oc2ncnc3c2nc(-c2cccc(OCCC(=O)O)c2Cl)n3Cc2cc(Cl)ccc2C#N)CC1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ EIF4EBP1 Q13541 18/20 0.33
▸ CNR1 P21554 1/20 0.33
▸ PIK3CD O00329 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31268752 0.92 PIK3CD (0.32) EIF4EBP1CNR1PIK3CD
SCHEMBL30983499 0.91 EIF4EBP1 (0.33) EIF4EBP1CNR1PIK3CD
SCHEMBL30983574 0.91 EIF4EBP1 (0.33) EIF4EBP1CNR1PIK3CD
SCHEMBL31269099 0.90 CNR1 (0.35) EIF4EBP1CNR1PIK3CD
SCHEMBL30983441 0.90 PDCD1 (0.36) PIK3CD
SCHEMBL31269437 0.90 PPARD (0.32) EIF4EBP1CNR1PIK3CD
SCHEMBL31269025 0.87 GPR119 (0.35) EIF4EBP1CNR1PIK3CD
SCHEMBL31269118 0.87 ACSL1 (0.36) EIF4EBP1CNR1PIK3CD
SCHEMBL31268897 0.87 PTGDR2 (0.36) CNR1PIK3CD
SCHEMBL30983968 0.86 CNR1 (0.36) CNR1PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689155-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS Astrazeneca AB (SE) 2026-02-11 — — EP disclosed
WO-2024201368-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS ASTRAZENECA AB (SE) 2024-10-03 — — WO disclosed
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