SCHEMBL31268820

SCHEMBL31268820

Cc1cnc(Cn2c(-c3ccc(OCCN(C)C)cc3Cl)nc3c(OC4(C)CC4)ncnc32)s1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ PIK3CD O00329 3/20 0.33
▸ TLR7 Q9NYK1 5/20 0.33
▸ IGF1R P08069 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31268797 0.96 TLR7 (0.33) PIK3CDTLR7IGF1R
SCHEMBL31269018 0.90 PIK3CD (0.33) PIK3CD
SCHEMBL31269206 0.89 PIK3CD (0.33) PIK3CD
SCHEMBL31269171 0.88 DRD2 (0.37) PIK3CDTLR7
SCHEMBL31269323 0.88 HRH4 (0.40) PIK3CDIGF1R
SCHEMBL31269378 0.86 PIK3CD (0.34) PIK3CD
SCHEMBL30983472 0.86 PDE2A (0.37) PIK3CD
SCHEMBL30984043 0.85 TLR7 (0.37) PIK3CDTLR7
SCHEMBL31268765 0.85 TLR7 (0.37) PIK3CDTLR7
SCHEMBL31269229 0.85 PIK3CD (0.33) PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689155-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS Astrazeneca AB (SE) 2026-02-11 — — EP disclosed
WO-2024201368-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS ASTRAZENECA AB (SE) 2024-10-03 — — WO disclosed
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