Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 7/20 | 0.35 |
| ▸ | CNR2 | P34972 | 5/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269247 | 0.94 | PIK3CD (0.34) | CNR1CNR2PIK3CDGRM5MEN1 | |
| SCHEMBL31269185 | 0.93 | CNR1 (0.38) | PDE4BCNR1CNR2PIK3CDGRM5 | |
| SCHEMBL31269264 | 0.91 | ABL1 (0.35) | CNR1CNR2PIK3CDGRM5MEN1 | |
| SCHEMBL31268823 | 0.89 | ABL1 (0.38) | CNR1CNR2PIK3CDKMT2A | |
| SCHEMBL31269416 | 0.89 | PIK3CD (0.33) | PDE4BPIK3CD | |
| SCHEMBL31269478 | 0.89 | SYK (0.36) | PIK3CDKCNH2SCN5ASCN9A | |
| SCHEMBL31269475 | 0.88 | PIK3CD (0.37) | PIK3CDKCNH2SCN5ASCN9A | |
| SCHEMBL31268954 | 0.87 | PIK3CD (0.35) | PIK3CDMEN1KMT2A | |
| SCHEMBL31269058 | 0.87 | PIK3CD (0.36) | CNR1CNR2PIK3CDKCNH2SCN5A | |
| SCHEMBL31268793 | 0.87 | PIK3CD (0.35) | CNR1CNR2PIK3CDKCNH2SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |