Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | POLB | P06746 | 5/20 | 0.71 |
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | DDX3X | O00571 | 1/20 | 0.68 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.56 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1880400 | 0.87 | POLB (0.68) | SMN1; SMN2KMT2AALDH1A1POLBMAPT | |
| SCHEMBL29838541 | 0.87 | POLB (0.68) | SMN1; SMN2KMT2AALDH1A1POLBMAPT | |
| SCHEMBL30434704 | 0.86 | KMT2A (0.82) | SMN1; SMN2KMT2AALDH1A1POLBMAPT | |
| SCHEMBL5455148 | 0.86 | KMT2A (0.82) | SMN1; SMN2KMT2AALDH1A1POLBMAPT | |
| SCHEMBL18940697 | 0.85 | KMT2A (0.79) | SMN1; SMN2KMT2AALDH1A1POLBMAPT | |
| SCHEMBL1248559 | 0.85 | SMN1; SMN2 (1.00) | SMN1; SMN2KMT2AALDH1A1POLBMAPT | |
| SCHEMBL12523964 | 0.85 | SMN1; SMN2 (0.76) | SMN1; SMN2KMT2AALDH1A1POLBMAPT | |
| SCHEMBL7865709 | 0.83 | SMN1; SMN2 (0.73) | SMN1; SMN2KMT2AALDH1A1POLBMAPT | |
| SCHEMBL11595071 | 0.83 | POLB (0.68) | SMN1; SMN2KMT2AALDH1A1POLBMAPT | |
| SCHEMBL6811011 | 0.82 | SMN1; SMN2 (0.81) | SMN1; SMN2KMT2AALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114956933-A | Marker containing isotope oxygen atom and preparation method and application thereof | 清华大学 | 2022-08-30 | — | — | CN | disclosed |
| EP-2945625-A2 | ANTI-VIRAL COMPOUNDS | Kineta, Inc. (US) | 2015-11-25 | — | — | EP | disclosed |
| WO-2014113492-A2 | ANTI-VIRAL COMPOUNDS | Kineta, Inc. (US) | 2014-07-24 | — | — | WO | disclosed |
| WO-2014113492-A2 | ANTI-VIRAL COMPOUNDS | Kineta, Inc. (US) | 2014-07-24 | — | — | WO | disclosed |
| WO-2010022055-A2 | INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | AMGEN INC. (US) | 2010-02-25 | — | — | WO | disclosed |
| US-4820332-A | Herbicidal sulfonamides | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1989-04-11 | — | — | US | disclosed |
| US-4643759-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-02-17 | — | — | US | disclosed |
| EP-0168264-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-01-15 | — | — | EP | disclosed |