Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.79 |
| ▸ | MAPT | P10636 | 7/20 | 0.73 |
| ▸ | POLB | P06746 | 4/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | DDX3X | O00571 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455148 | 0.98 | KMT2A (0.82) | KMT2AALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL30434704 | 0.98 | KMT2A (0.82) | KMT2AALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL5448052 | 0.93 | ALDH1A1 (0.75) | KMT2AALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL30542218 | 0.92 | ALDH1A1 (0.73) | KMT2AALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL31492044 | 0.89 | KMT2A (0.73) | KMT2AALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL6819562 | 0.88 | KMT2A (0.72) | KMT2AALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL6811011 | 0.87 | SMN1; SMN2 (0.81) | KMT2AALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL29838541 | 0.85 | POLB (0.68) | KMT2AALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL3126901 | 0.85 | SMN1; SMN2 (0.73) | KMT2AALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL1880400 | 0.85 | POLB (0.68) | KMT2AALDH1A1MAPTPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9884812-B2 | Use of DDX3X inhibitors for the treatment of pneumovirus infections | UNIVERSITY OF WARWICK (GB) | 2018-02-06 | — | — | US | disclosed |
| US-20170166519-A1 | USE OF DDX3X INHIBITORS FOR THE TREATMENT OF PNEUMOVIRUS INFECTIONS | UNIVERSITY OF WARWICK (GB) | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170166519-A1 | USE OF DDX3X INHIBITORS FOR THE TREATMENT OF PNEUMOVIRUS INFECTIONS | DDX3X, DDX1, DDX5 | KMT2A 2069/4885ALDH1A1 2833/4885MAPT 3569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.