Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | LYN | P07948 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.30 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31268817 | 0.96 | KCNH2 (0.38) | KCNH2SCN5ASCN9APIK3CDPDE2A | |
| SCHEMBL31269467 | 0.94 | KCNH2 (0.34) | KCNH2SCN5ASCN9APIK3CD | |
| SCHEMBL31269000 | 0.94 | PDE2A (0.39) | KCNH2SCN5ASCN9APIK3CDPDE2A | |
| SCHEMBL31268776 | 0.91 | KCNH2 (0.41) | KCNH2SCN5ASCN9APIK3CDPDE2A | |
| SCHEMBL31269094 | 0.90 | PDK2 (0.37) | KCNH2SCN5ASCN9APIK3CDHRH3 | |
| SCHEMBL31269371 | 0.89 | KCNH2 (0.36) | KCNH2SCN5ASCN9APIK3CDPDE2A | |
| SCHEMBL31269101 | 0.89 | KCNH2 (0.36) | KCNH2SCN5ASCN9APIK3CDHRH3 | |
| SCHEMBL31269003 | 0.89 | HRH4 (0.36) | KCNH2SCN5ASCN9APIK3CDHRH3 | |
| SCHEMBL31268859 | 0.87 | SIGMAR1 (0.38) | KCNH2SCN5ASCN9APIK3CD | |
| SCHEMBL31269300 | 0.87 | DGAT1 (0.41) | KCNH2SCN5ASCN9APIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |