Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAVCR2 | Q8TDQ0 | 3/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | KIT | P10721 | 2/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269244 | 0.88 | KMT2A (0.34) | PIK3CDSCN9AKCNH2SCN5ASCN8A | |
| SCHEMBL31269047 | 0.88 | PIK3CD (0.36) | PIK3CDSCN9AKCNH2SCN5ACNR1 | |
| SCHEMBL31269106 | 0.87 | INSR (0.32) | PIK3CDSCN9AKCNH2SCN5ACNR1 | |
| SCHEMBL31269266 | 0.86 | PIK3CD (0.35) | PIK3CDSCN9AKCNH2SCN5ACNR1 | |
| SCHEMBL31269032 | 0.86 | PARG (0.37) | PIK3CDSCN9AKCNH2SCN5ACNR1 | |
| SCHEMBL31268908 | 0.86 | KCNJ5 (0.33) | PIK3CDCNR1CNR2 | |
| SCHEMBL31268984 | 0.86 | PIK3CD (0.33) | PIK3CDSCN9AKCNH2SCN5ASCN8A | |
| SCHEMBL31268946 | 0.86 | PIK3CD (0.34) | PIK3CDSCN9AKCNH2SCN5A | |
| SCHEMBL31269202 | 0.85 | POLB (0.31) | PIK3CDSCN9AKCNH2SCN5A | |
| SCHEMBL30983829 | 0.85 | KCNH2 (0.34) | PIK3CDSCN9AKCNH2SCN5ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |