Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.36 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269266 | 0.92 | PIK3CD (0.35) | PIK3CDAGPAT2NPC1LMNAKDR | |
| SCHEMBL31269321 | 0.92 | PIK3CD (0.34) | PIK3CDHSD11B1KCNH2SCN5ASCN9A | |
| SCHEMBL31269339 | 0.91 | PIK3CD (0.34) | PIK3CDAGPAT2HSD11B1KCNH2SCN5A | |
| SCHEMBL31269219 | 0.90 | PIK3CD (0.33) | PIK3CDALDH1A1NPC1LMNAKDR | |
| SCHEMBL31268904 | 0.89 | PIK3CD (0.41) | PIK3CDLMNACNR1CNR2MAPT | |
| SCHEMBL31268946 | 0.89 | PIK3CD (0.34) | PIK3CDALDH1A1SMN1; SMN2KCNH2SCN5A | |
| SCHEMBL31269077 | 0.88 | HAVCR2 (0.33) | PIK3CDKCNH2SCN5ASCN9ACNR1 | |
| SCHEMBL31269475 | 0.87 | PIK3CD (0.37) | PIK3CDHSD11B1KCNH2SCN5ASCN9A | |
| SCHEMBL30983779 | 0.86 | KCNH2 (0.36) | PIK3CDKCNH2SCN5ASCN9ACNR1 | |
| SCHEMBL31269478 | 0.86 | SYK (0.36) | PIK3CDKCNH2SCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |