Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 4/20 | 0.36 |
| ▸ | PDE2A | O00408 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269305 | 0.96 | HRH4 (0.42) | ESR1ESR2HRH4KDM4EPOLB | |
| SCHEMBL30983467 | 0.94 | PDE2A (0.38) | ESR1ESR2HRH4DRD2PDE2A | |
| SCHEMBL31269218 | 0.91 | THRB (0.38) | HRH4KDM4E | |
| SCHEMBL30983862 | 0.91 | KCNH2 (0.33) | ESR1ESR2HRH4DRD2 | |
| SCHEMBL30983456 | 0.89 | PIK3CD (0.35) | HRH4PDE2ATLR7 | |
| SCHEMBL31268950 | 0.89 | KCNH2 (0.32) | HRH4TLR7 | |
| SCHEMBL31269061 | 0.89 | MET (0.33) | HRH4PDE2ATLR7 | |
| SCHEMBL30984004 | 0.89 | KCNH2 (0.32) | HRH4 | |
| SCHEMBL31269101 | 0.89 | KCNH2 (0.36) | — | |
| SCHEMBL31269189 | 0.89 | HRH4 (0.33) | HRH4PDE2ATLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |