Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | WDR5 | P61964 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31268860 | 0.93 | TDP1 (0.33) | PIK3CDWNT3ATDP1MAPTLMNA | |
| SCHEMBL31269356 | 0.92 | PIK3CD (0.35) | PIK3CDWNT3ATDP1MAPTKCNH2 | |
| SCHEMBL31268967 | 0.90 | PIK3CD (0.33) | PIK3CDWNT3ATDP1MAPTKCNH2 | |
| SCHEMBL31269369 | 0.90 | PIK3CD (0.35) | PIK3CDWNT3AKCNH2SCN5ASCN9A | |
| SCHEMBL31269392 | 0.90 | PIK3CD (0.34) | PIK3CDMAPT | |
| SCHEMBL31268746 | 0.90 | PIK3CD (0.33) | PIK3CDWNT3ATDP1KCNH2SCN5A | |
| SCHEMBL31269404 | 0.90 | KEAP1 (0.34) | PIK3CDWNT3AKCNH2SCN5ASCN9A | |
| SCHEMBL31269254 | 0.89 | PIK3CD (0.33) | PIK3CDWNT3ATDP1KCNH2SCN5A | |
| SCHEMBL31269146 | 0.89 | PIK3CD (0.35) | PIK3CDWDR5 | |
| SCHEMBL30984050 | 0.88 | PIK3CD (0.36) | PIK3CDWNT3AKCNH2SCN5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |