SCHEMBL31269161

SCHEMBL31269161

CN(C)CCCOc1ccc(-c2nc3c(OC4(C)CC4)ncnc3n2Cc2cc(C(F)F)ccn2)c(Cl)c1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TLR7 Q9NYK1 4/20 0.34
▸ PIK3CD O00329 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30984070 0.90 TLR7 (0.34) TLR7PIK3CD
SCHEMBL31269450 0.90 TLR7 (0.34) TLR7PIK3CD
SCHEMBL31269155 0.89 TLR7 (0.34) TLR7PIK3CD
SCHEMBL31268920 0.88 HRH4 (0.33) PIK3CD
SCHEMBL31268922 0.87 PDE2A (0.36) —
SCHEMBL31268971 0.87 PIK3CD (0.31) PIK3CD
SCHEMBL31268765 0.87 TLR7 (0.37) TLR7PIK3CD
SCHEMBL30984043 0.87 TLR7 (0.37) TLR7PIK3CD
SCHEMBL31269220 0.85 TLR7 (0.38) TLR7PIK3CD
SCHEMBL31268985 0.84 TLR7 (0.34) TLR7PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689155-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS Astrazeneca AB (SE) 2026-02-11 — — EP disclosed
WO-2024201368-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS ASTRAZENECA AB (SE) 2024-10-03 — — WO disclosed
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