SCHEMBL31268971

SCHEMBL31268971

CC1(Oc2ncnc3c2nc(-c2ccc(OCCN4CC(O)C4)cc2Cl)n3Cc2cc(C(F)F)ccn2)CC1

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ PIK3CD O00329 1/20 0.31
▸ MEN1 O00255 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31268920 0.97 HRH4 (0.33) PIK3CD
SCHEMBL31268906 0.92 HRH3 (0.34) PIK3CD
SCHEMBL31269269 0.91 DRD2 (0.33) PIK3CDMEN1KMT2A
SCHEMBL30983862 0.91 KCNH2 (0.33) PIK3CDMEN1KMT2A
SCHEMBL31269042 0.90 DRD2 (0.38) PIK3CDMEN1KMT2A
SCHEMBL31268922 0.89 PDE2A (0.36) —
SCHEMBL31268792 0.88 HRH4 (0.35) PIK3CD
SCHEMBL31269258 0.88 HRH4 (0.36) PIK3CD
SCHEMBL31269161 0.87 TLR7 (0.34) PIK3CD
SCHEMBL31268977 0.87 DRD2 (0.34) PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689155-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS Astrazeneca AB (SE) 2026-02-11 — — EP disclosed
WO-2024201368-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS ASTRAZENECA AB (SE) 2024-10-03 — — WO disclosed
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