Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31269338 | 0.93 | PIK3CD (0.33) | PIK3CDCNR1GPBAR1KCNH2SCN5A | |
| SCHEMBL31268764 | 0.92 | PIK3CD (0.33) | PIK3CDCNR1GPBAR1KCNH2SCN5A | |
| SCHEMBL31269059 | 0.89 | PIK3CD (0.34) | PIK3CDCNR1CNR2MTNR1AMTNR1B | |
| SCHEMBL31268930 | 0.89 | KCNH2 (0.34) | PIK3CDCNR1KCNH2SCN5ASCN9A | |
| SCHEMBL31268953 | 0.89 | PDK2 (0.33) | PIK3CDCNR1CNR2 | |
| SCHEMBL31269106 | 0.88 | INSR (0.32) | PIK3CDCNR1CNR2KCNH2SCN5A | |
| SCHEMBL31269187 | 0.88 | PIK3CD (0.34) | PIK3CDKCNH2SCN5ASCN9AMAPT | |
| SCHEMBL31268981 | 0.88 | PIK3CD (0.35) | PIK3CDCNR1CNR2KCNH2SCN5A | |
| SCHEMBL30984050 | 0.87 | PIK3CD (0.36) | PIK3CDCNR1CNR2KCNH2SCN5A | |
| SCHEMBL31268967 | 0.87 | PIK3CD (0.33) | PIK3CDKCNH2SCN5ASCN9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |