SCHEMBL31269237

SCHEMBL31269237

CC1(Oc2ncnc3c2nc(-c2ccc(OCCO)cc2Cl)n3Cc2cc(C(F)(F)F)ccn2)CC1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ DRD2 P14416 3/20 0.34
▸ RAF1 P04049 6/20 0.34
▸ PIK3CD O00329 4/20 0.34
▸ PDE2A O00408 1/20 0.32
▸ PDE10A Q9Y233 1/20 0.32
▸ BRAF P15056 3/20 0.31
▸ ACACB O00763 1/20 0.31
▸ HCRTR1 O43613 2/20 0.31
▸ HCRTR2 O43614 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31268966 0.96 DRD2 (0.34) DRD2RAF1PIK3CDPDE2APDE10A
SCHEMBL31269155 0.91 TLR7 (0.34) DRD2PIK3CD
SCHEMBL31269351 0.91 PIK3CD (0.35) PIK3CDPDE2APDE10A
SCHEMBL30983456 0.91 PIK3CD (0.35) PIK3CDPDE2APDE10A
SCHEMBL31269042 0.90 DRD2 (0.38) DRD2PIK3CDACACB
SCHEMBL31268977 0.89 DRD2 (0.34) DRD2PIK3CD
SCHEMBL30983576 0.88 DRD2 (0.41) DRD2PIK3CDPDE2A
SCHEMBL31268935 0.87 PDE2A (0.34) PIK3CDPDE2APDE10A
SCHEMBL31269005 0.87 PDE2A (0.35) PIK3CDPDE2APDE10A
SCHEMBL31268917 0.87 PIK3CD (0.32) PIK3CDPDE2APDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689155-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS Astrazeneca AB (SE) 2026-02-11 — — EP disclosed
WO-2024201368-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS ASTRAZENECA AB (SE) 2024-10-03 — — WO disclosed
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