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Sugi Predict / Compounds / SCHEMBL31269042

SCHEMBL31269042

SCHEMBL31269042

CC1(Oc2ncnc3c2nc(-c2ccc(OCCN4CC(O)C4)cc2Cl)n3Cc2cc(C(F)(F)F)ccn2)CC1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ DRD2 P14416 8/20 0.38
▸ PIK3CD O00329 5/20 0.34
▸ PDK2 Q15119 2/20 0.33
▸ ACACB O00763 1/20 0.30
▸ MEN1 O00255 1/20 0.30
▸ KMT2A Q03164 1/20 0.30
▸ KDR P35968 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31268977 0.97 DRD2 (0.34) DRD2PIK3CD
SCHEMBL31269269 0.92 DRD2 (0.33) DRD2PIK3CDMEN1KMT2A
SCHEMBL30983862 0.92 KCNH2 (0.33) DRD2PIK3CDMEN1KMT2A
SCHEMBL31269384 0.92 PDK2 (0.37) DRD2PIK3CDPDK2
SCHEMBL31268971 0.90 PIK3CD (0.31) PIK3CDMEN1KMT2A
SCHEMBL31269237 0.90 DRD2 (0.34) DRD2PIK3CDACACB
SCHEMBL30983576 0.89 DRD2 (0.41) DRD2PIK3CD
SCHEMBL31268966 0.89 DRD2 (0.34) DRD2PIK3CDACACBKDR
SCHEMBL31268792 0.88 HRH4 (0.35) PIK3CD
SCHEMBL31269258 0.88 HRH4 (0.36) PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689155-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS Astrazeneca AB (SE) 2026-02-11 — — EP disclosed
WO-2024201368-A1 USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS ASTRAZENECA AB (SE) 2024-10-03 — — WO disclosed
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