Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | PDE8B | O95263 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984035 | 0.96 | ADORA2A (0.42) | ADORA2AADORA1ALDH1A1KDM4ETSHR | |
| SCHEMBL30984102 | 0.81 | ADORA2A (0.56) | ADORA2AADORA1TMIGD3ADORA2B | |
| SCHEMBL30984101 | 0.81 | ADORA2A (0.56) | ADORA2AADORA1TMIGD3ADORA2B | |
| Lithium SCHEMBL30983994 | 0.80 | ADORA2A (0.55) | ADORA2AADORA1TMIGD3ADORA2B | |
| SCHEMBL31321972 | 0.65 | PIK3CD (0.38) | ADORA2AADORA1 | |
| SCHEMBL5732024 | 0.63 | ADORA2A (0.65) | ADORA2AADORA1KDM4ETSHRHSD17B10 | |
| SCHEMBL7204696 | 0.63 | ADORA2A (0.61) | ADORA2AADORA1ALDH1A1KDM4EHPGD | |
| SCHEMBL7205701 | 0.63 | ADORA2A (0.61) | ADORA2AADORA1TLR7TMIGD3ADORA2B | |
| SCHEMBL7204601 | 0.63 | ADORA2A (0.60) | ADORA2AADORA1ALDH1A1HPGDLMNA | |
| SCHEMBL2060194 | 0.63 | TLR7 (0.55) | ADORA2AADORA1TLR7TMIGD3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |