Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.55 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30984101 | 0.99 | ADORA2A (0.56) | ADORA2AADORA1TMIGD3ADORA2BPIK3CD | |
| SCHEMBL30984102 | 0.99 | ADORA2A (0.56) | ADORA2AADORA1TMIGD3ADORA2BPIK3CD | |
| SCHEMBL31269259 | 0.80 | ADORA2A (0.41) | ADORA2AADORA1TMIGD3ADORA2B | |
| SCHEMBL30983805 | 0.78 | PIK3CD (0.41) | ADORA2AADORA1PIK3CD | |
| SCHEMBL30983811 | 0.78 | DAPK1 (0.62) | ADORA2A | |
| SCHEMBL30983784 | 0.77 | PIK3CD (0.40) | ADORA2AADORA1PIK3CD | |
| SCHEMBL31269114 | 0.76 | DAPK1 (0.60) | ADORA2A | |
| SCHEMBL30984035 | 0.75 | ADORA2A (0.42) | ADORA2AADORA1TMIGD3ADORA2B | |
| SCHEMBL30983819 | 0.74 | ADORA2A (0.36) | ADORA2AADORA1ADORA2BPIK3CD | |
| SCHEMBL30983894 | 0.73 | DAPK1 (0.65) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121753-A1 | POLQ INHIBITORS | ASTRAZENECA AB (SE) | 2024-06-13 | — | — | WO | disclosed |