Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31268798 | 0.92 | MEN1 (0.34) | SMN1; SMN2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL31269100 | 0.90 | PIK3CD (0.34) | PIK3CD | |
| SCHEMBL31268949 | 0.89 | PIK3CD (0.35) | PIK3CD | |
| SCHEMBL31269257 | 0.88 | PIK3CD (0.36) | SMN1; SMN2NPC1RAB9AKMT2APIK3CD | |
| SCHEMBL31269024 | 0.87 | PIK3CD (0.33) | MEN1KMT2APIK3CD | |
| SCHEMBL31269355 | 0.87 | PIK3CD (0.38) | SMN1; SMN2NPC1RAB9AKMT2APIK3CD | |
| SCHEMBL31269275 | 0.87 | KDM4E (0.35) | PIK3CD | |
| SCHEMBL31269396 | 0.87 | PIK3CD (0.33) | PIK3CD | |
| SCHEMBL31268819 | 0.87 | PIK3CD (0.36) | PIK3CD | |
| SCHEMBL31269207 | 0.86 | PIK3CD (0.38) | SMN1; SMN2NPC1RAB9AKMT2APIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4689155-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | Astrazeneca AB (SE) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024201368-A1 | USE OF INHIBITORS TO INCREASE EFFICIENCY OF CRISPR/CAS INSERTIONS | ASTRAZENECA AB (SE) | 2024-10-03 | — | — | WO | disclosed |