Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 6/20 | 0.49 |
| ▸ | IDO1 | P14902 | 4/20 | 0.48 |
| ▸ | AGXT | P21549 | 4/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29442637 | 0.86 | TDP1 (0.48) | TDP1L3MBTL1MAOBIDO1AGXT | |
| SCHEMBL12951814 | 0.86 | TDP1 (0.48) | TDP1L3MBTL1MAOBIDO1AGXT | |
| SCHEMBL28360324 | 0.86 | TDP1 (0.48) | TDP1L3MBTL1MAOBIDO1AGXT | |
| Anisole SCHEMBL14879816 | 0.83 | TSHR (0.60) | TDP1L3MBTL1MAOBIDO1AGXT | |
| SCHEMBL12526332 | 0.83 | MAOB (0.62) | TDP1L3MBTL1MAOBIDO1AGXT | |
| SCHEMBL5250014 | 0.83 | APP (0.53) | TDP1L3MBTL1MAOBIDO1AGXT | |
| SCHEMBL4507875 | 0.83 | APP (0.53) | TDP1L3MBTL1MAOBIDO1AGXT | |
| SCHEMBL10820376 | 0.83 | MAOB (0.67) | TDP1MAOBRAB9ATP53PKM | |
| SCHEMBL28551906 | 0.83 | LTA4H (0.69) | TDP1L3MBTL1MAOBIDO1AGXT | |
| SCHEMBL6429953 | 0.83 | LTA4H (0.69) | TDP1L3MBTL1MAOBIDO1AGXT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170349520-A1 | SINGLY PROTECTED 2,2' -DIHYDROXYBIARYLS | EVONIK DEGUSSA GMBH (DE) | 2017-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170349520-A1 | SINGLY PROTECTED 2,2' -DIHYDROXYBIARYLS | DBH, COMT, DRD2 | TDP1 2320/4885L3MBTL1 2683/4885MAOB 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.