Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.33 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31745069 | 0.76 | NOS3 (0.38) | GRIN3BGRIN1GRIN2CNR4A2SOS2 | |
| SCHEMBL31269801 | 0.75 | ROCK1 (0.34) | NCF1NOS3NOS2FBP1 | |
| SCHEMBL29564856 | 0.72 | NCF1 (0.41) | MEN1NR4A2SOS2NCF1NOS3 | |
| Trifluoroacetic Acid SCHEMBL31745042 | 0.72 | HTT (0.36) | GRIN3BGRIN1GRIN2C | |
| SCHEMBL31745001 | 0.72 | NCF1 (0.37) | NR4A2SOS2NCF1 | |
| SCHEMBL30317201 | 0.72 | NCF1 (0.37) | NR4A2NCF1FBP1 | |
| SCHEMBL30317218 | 0.72 | NCF1 (0.37) | MEN1NR4A2NCF1 | |
| SCHEMBL30317422 | 0.72 | NR4A2 (0.33) | NR4A2SOS2NCF1 | |
| Hydrochloric Acid SCHEMBL29565618 | 0.71 | NCF1 (0.39) | NR4A2SOS2NCF1 | |
| Hydrochloric Acid SCHEMBL22346307 | 0.71 | NCF1 (0.36) | NR4A2NCF1FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400591-A1 | COMPOUNDS TARGETING MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2024-12-05 | — | — | US | claimed |
| US-20240400591-A1 | COMPOUNDS TARGETING MUTANT OF P53 | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2024-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400591-A1 | COMPOUNDS TARGETING MUTANT OF P53 | TP53, TP53BP1, MDM2 | MEN1 3802/4885GRIN3B 3851/4885GRIN1 3786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.