SCHEMBL31270594

SCHEMBL31270594

Cc1cc(C)nc(SCC(=O)c2ccc(O)c(O)c2)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALPG P10696 4/20 1.00
ALPL P05186 3/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
POLB P06746 2/20 1.00
ALPI P09923 1/20 1.00
PLAA Q9Y263 1/20 1.00
HPGD P15428 3/20 0.70
TSHR P16473 1/20 0.70
HSD17B10 Q99714 1/20 0.70
PIM1 P11309 1/20 0.67
CA12 O43570 4/20 0.65
CA1 P00915 4/20 0.65
CA2 P00918 4/20 0.65
CA6 P23280 4/20 0.65
CA7 P43166 4/20 0.65
CA13 Q8N1Q1 4/20 0.65
GAA P10253 2/20 0.64
HSP90AA1 P07900 1/20 0.64
HSP90AB1 P08238 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21954102 0.83 POLB (0.70) ALPGALPLMEN1KMT2APOLB
SCHEMBL18805093 0.79 ALPG (0.65) ALPGALPLMEN1KMT2APOLB
SCHEMBL17382815 0.79 HDAC6 (1.00) ALPGALPLMEN1KMT2APOLB
SCHEMBL14434190 0.79 ALPG (0.69) ALPGALPLMEN1KMT2APOLB
SCHEMBL18425027 0.77 CA1 (1.00) ALPGALPLMEN1KMT2APOLB
SCHEMBL18805092 0.77 KLF10 (0.84) ALPGALPLMEN1KMT2APOLB
SCHEMBL13856739 0.76 POLB (0.64) ALPGALPLMEN1KMT2APOLB
SCHEMBL2534105 0.76 ALPL (1.00) ALPGALPLMEN1KMT2APOLB
SCHEMBL8258568 0.74 ALPG (0.58) ALPGALPLMEN1KMT2APOLB
SCHEMBL13401667 0.72 HDAC3 (0.61) ALPGALPLMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4492059-A2 METHODS OF MODULATING ANTIGENICITY TO ENHANCE RECOGNITION BY T-CELLS THE GENERAL HOSPITAL CORPORATION (US) 2025-01-15 EP disclosed