Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26990021 | 0.88 | HPGD (0.51) | ARHPGDMAPTALDH1A1KDM4E | |
| SCHEMBL28725597 | 0.85 | MAPT (0.55) | ARHPGDMAPTALDH1A1KDM4E | |
| SCHEMBL7826262 | 0.82 | ALDH1A1 (0.49) | HPGDMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL3121764 | 0.81 | ALDH1A1 (0.57) | HPGDMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL1946478 | 0.78 | MEN1 (0.50) | HPGDMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL4395535 | 0.78 | MAPT (0.49) | HPGDMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL3124302 | 0.75 | MAPT (0.58) | ARHPGDMAPTALDH1A1KDM4E | |
| SCHEMBL5232416 | 0.74 | HDAC3 (0.45) | MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL7860579 | 0.74 | AR (0.56) | ARMAPTALDH1A1KDM4ELMNA | |
| SCHEMBL3121805 | 0.72 | PRKDC (0.48) | MAPTALDH1A1KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001126-A1 | THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2010-01-07 | — | — | WO | disclosed |
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | disclosed |