Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26990021 | 0.83 | HPGD (0.51) | MAPTALDH1A1RAB9AARMEN1 | |
| SCHEMBL3127062 | 0.75 | AR (0.50) | MAPTALDH1A1RAB9AARMEN1 | |
| SCHEMBL28725597 | 0.74 | MAPT (0.55) | MAPTALDH1A1RAB9AARMEN1 | |
| SCHEMBL4395535 | 0.71 | MAPT (0.49) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| (2-Chlorophenyl)(Morpholino)Methanone SCHEMBL6938284 | 0.69 | MGLL (0.68) | MAPTALDH1A1RAB9AMGLLKMT2A | |
| Hydrochloric Acid SCHEMBL10333813 | 0.68 | ALDH1A1 (0.50) | ALDH1A1RECQLLMNAGAA | |
| SCHEMBL3121764 | 0.68 | ALDH1A1 (0.57) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL28916553 | 0.67 | MGLL (0.64) | ALDH1A1RAB9AMGLLMEN1KMT2A | |
| (2-Chlorophenyl)(Morpholino)Methanone SCHEMBL4648775 | 0.66 | MGLL (0.62) | MAPTALDH1A1RAB9AMGLLKMT2A | |
| SCHEMBL1946478 | 0.66 | MEN1 (0.50) | MAPTALDH1A1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010001126-A1 | THIOPHENE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA S.A. (BE) | 2010-01-07 | — | — | WO | disclosed |