Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.50 |
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | CA12 | O43570 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP3A43 | Q9HB55 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31270840 | 0.96 | CA12 (0.51) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL18544360 | 0.96 | CA12 (0.49) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL31271052 | 0.96 | CA12 (0.49) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL24838619 | 0.90 | ADRB2 (0.45) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL18569779 | 0.90 | ADRB2 (0.45) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL25457307 | 0.87 | CA12 (0.46) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL18544363 | 0.87 | ALDH1A1 (0.53) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL18544318 | 0.86 | ALDH1A1 (0.50) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL18544342 | 0.84 | CA12 (0.46) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL18570051 | 0.84 | APP (0.52) | CA1CA2CA12CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220676-A1 | MRNA DEGRADERS AND METHODS OF USE THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-10-24 | — | — | WO | disclosed |