SCHEMBL31270758

SCHEMBL31270758

CC(C)(C)OC(=O)N1CCC(Cc2ccc(CN3CCOCC3)cc2)CC1

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.61
RECQL P46063 1/20 0.51
USP2 O75604 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
TP53 P04637 4/20 0.47
KDM4E B2RXH2 1/20 0.47
PKM P14618 1/20 0.47
GPR119 Q8TDV5 3/20 0.46
HRH3 Q9Y5N1 3/20 0.46
LMNA P02545 2/20 0.45
MAPT P10636 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4767971 0.87 GPR119 (0.60) RECQLUSP2SMN1; SMN2GPR119LMNA
SCHEMBL3020170 0.86 RECQL (0.51) RECQLUSP2SMN1; SMN2TP53GPR119
SCHEMBL5205491 0.84 HRH3 (0.60) RECQLUSP2SMN1; SMN2GPR119HRH3
SCHEMBL7845430 0.84 ALDH1A1 (0.62) RECQLUSP2SMN1; SMN2KDM4EHRH3
SCHEMBL3155704 0.83 STS (0.56) GAAUSP2SMN1; SMN2TP53KDM4E
SCHEMBL22532739 0.83 KDM4E (0.52) TP53KDM4EPKMGPR119LMNA
SCHEMBL1722245 0.82 SMN1; SMN2 (0.57) USP2SMN1; SMN2GPR119HRH3LMNA
SCHEMBL16113579 0.82 GPR119 (0.61) SMN1; SMN2TP53KDM4EPKMGPR119
SCHEMBL12263494 0.82 KDM4E (0.53) TP53KDM4EPKMGPR119
SCHEMBL2250178 0.82 GPR119 (0.60) TP53KDM4EPKMGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4719384-A2 COMPOUNDS WITH ANTIFUNGAL PROPERTIES Trustees of Dartmouth College (US) 2026-04-08 EP disclosed
WO-2024249290-A2 COMPOUNDS WITH ANTIFUNGAL PROPERTIES TRUSTEES OF DARTMOUTH COLLEGE (US) 2024-12-05 WO disclosed