Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31270901 | 0.97 | CA12 (0.43) | CA12CA2CA14TDP1CTSL | |
| SCHEMBL31271463 | 0.86 | CTSS (0.40) | CA12CA2TDP1CTSLCTSB | |
| SCHEMBL9055377 | 0.85 | CA12 (0.46) | CA12CA2CA14TDP1MAOA | |
| SCHEMBL1456111 | 0.83 | MEN1 (0.41) | CA12CA2CA14TDP1CTSL | |
| SCHEMBL20807173 | 0.82 | TDP1 (0.44) | CA12CA2CA14TDP1MAOA | |
| SCHEMBL21071237 | 0.81 | KDM4E (0.37) | CA12CA2CA14CTSLCTSB | |
| SCHEMBL21070174 | 0.81 | KDM4E (0.37) | CA12CA2CA14CTSLCTSB | |
| SCHEMBL21887790 | 0.79 | MEN1 (0.43) | CA12CA2CA14TDP1CTSL | |
| SCHEMBL523837 | 0.78 | CA2 (0.59) | CA12CA2CA14TDP1MAOA | |
| SCHEMBL409603 | 0.78 | CA12 (0.40) | CA12CA2CA14TDP1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220676-A1 | MRNA DEGRADERS AND METHODS OF USE THEREOF | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2024-10-24 | — | — | WO | disclosed |