Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 15/20 | 0.53 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31271175 | 0.85 | GPR119 (0.58) | GPR119USP30RET | |
| SCHEMBL31271887 | 0.82 | GPR119 (0.53) | GPR119JAK3RET | |
| SCHEMBL22777328 | 0.81 | GPR119 (0.59) | GPR119USP30RET | |
| SCHEMBL31271007 | 0.80 | GPR119 (0.56) | GPR119JAK3RET | |
| SCHEMBL24962301 | 0.79 | GPR119 (0.57) | GPR119RET | |
| SCHEMBL16651945 | 0.79 | GPR119 (0.54) | GPR119 | |
| SCHEMBL31271149 | 0.78 | GPR119 (0.54) | GPR119USP30RET | |
| SCHEMBL29704261 | 0.76 | GPR119 (0.54) | GPR119JAK3RET | |
| SCHEMBL16110048 | 0.75 | GPR119 (0.60) | GPR119USP30 | |
| SCHEMBL16110050 | 0.75 | GPR119 (0.60) | GPR119USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024249950-A1 | FUSED PYRIMIDINE COMPOUNDS AS INHIBITORS OF MENIN | BIOMEA FUSION, INC. (US) | 2024-12-05 | — | — | WO | disclosed |