SCHEMBL31271503

SCHEMBL31271503

Nc1nc(Nc2ccccc2)n(Cc2cccc(Br)c2)n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.49
MAPT P10636 2/20 0.49
KMT2A Q03164 2/20 0.49
LMNA P02545 1/20 0.49
HTT P42858 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
KDR P35968 4/20 0.46
FLT1 P17948 3/20 0.46
TP53 P04637 1/20 0.44
PDGFRB P09619 2/20 0.42
APP P05067 2/20 0.42
EGFR P00533 3/20 0.42
KCNJ6 P48051 2/20 0.41
KCNJ5 P48544 2/20 0.41
KCNJ3 P48549 2/20 0.41
FAAH O00519 1/20 0.40
POLB P06746 1/20 0.40
GALR3 O60755 1/20 0.40
GAA P10253 1/20 0.40
NPY1R P25929 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31271953 0.93 MEN1 (0.43) MEN1MAPTKMT2ALMNAHTT
SCHEMBL31271744 0.89 MEN1 (0.48) MEN1MAPTKMT2ALMNAHTT
SCHEMBL31272070 0.89 KDR (0.44) MEN1MAPTKMT2ALMNAHTT
SCHEMBL31271506 0.87 MET (0.47) MEN1MAPTKMT2ALMNAHTT
SCHEMBL12780749 0.85 CXCR2 (0.47) MEN1MAPTKMT2ALMNASMN1; SMN2
SCHEMBL31272178 0.83 RAB9A (0.44) MEN1MAPTKMT2ALMNASMN1; SMN2
SCHEMBL31272017 0.82 IDH2 (0.47) MEN1MAPTKMT2ALMNASMN1; SMN2
SCHEMBL31271824 0.82 NR1H2 (0.49) MEN1MAPTKMT2ALMNATP53
SCHEMBL31271710 0.80 MEN1 (0.46) MEN1MAPTKMT2ALMNAHTT
SCHEMBL17731599 0.78 MEN1 (0.48) MEN1MAPTKMT2ALMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698519-A1 3,5-DIAMINOTRIAZOLE DERIVATIVES AND USES THEREOF FOR TREATING OCULAR DISEASES Centre National de la Recherche Scientifique (FR) 2026-02-25 EP claimed
WO-2024218236-A1 3,5-DIAMINOTRIAZOLE DERIVATIVES AND USES THEREOF FOR TREATING OCULAR DISEASES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2024-10-24 WO claimed
EP-4698519-A1 3,5-DIAMINOTRIAZOLE DERIVATIVES AND USES THEREOF FOR TREATING OCULAR DISEASES Centre National de la Recherche Scientifique (FR) 2026-02-25 EP disclosed
WO-2024218236-A1 3,5-DIAMINOTRIAZOLE DERIVATIVES AND USES THEREOF FOR TREATING OCULAR DISEASES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2024-10-24 WO disclosed