Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12780738 | 0.91 | JAK2 (0.49) | MAPTKMT2AMEN1SMN1; SMN2MET | |
| SCHEMBL31272222 | 0.88 | NPC1 (0.47) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL31272189 | 0.87 | MET (0.45) | MAPTKMT2AMEN1SMN1; SMN2MET | |
| SCHEMBL31272639 | 0.84 | POLB (0.45) | MAPTKMT2AMEN1METJAK2 | |
| SCHEMBL17366559 | 0.84 | ALDH1A1 (0.49) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL31271561 | 0.82 | JAK2 (0.53) | MAPTKMT2AMEN1JAK2ALDH1A1 | |
| SCHEMBL31271424 | 0.82 | KDM4E (0.48) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL31272106 | 0.81 | JAK2 (0.45) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL31271747 | 0.81 | JAK2 (0.49) | KMT2AMEN1SMN1; SMN2METJAK2 | |
| SCHEMBL31272160 | 0.81 | JAK1 (0.48) | KMT2AMETJAK2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4698519-A1 | 3,5-DIAMINOTRIAZOLE DERIVATIVES AND USES THEREOF FOR TREATING OCULAR DISEASES | Centre National de la Recherche Scientifique (FR) | 2026-02-25 | — | — | EP | claimed |
| WO-2024218236-A1 | 3,5-DIAMINOTRIAZOLE DERIVATIVES AND USES THEREOF FOR TREATING OCULAR DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2024-10-24 | — | — | WO | claimed |
| EP-4698519-A1 | 3,5-DIAMINOTRIAZOLE DERIVATIVES AND USES THEREOF FOR TREATING OCULAR DISEASES | Centre National de la Recherche Scientifique (FR) | 2026-02-25 | — | — | EP | disclosed |
| WO-2024218236-A1 | 3,5-DIAMINOTRIAZOLE DERIVATIVES AND USES THEREOF FOR TREATING OCULAR DISEASES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2024-10-24 | — | — | WO | disclosed |