Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 7/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.78 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.55 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.55 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.55 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.51 |
| ▸ | TDP2 | O95551 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL875772 | 1.00 | PDE7A (0.78) | PDE7ASMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1342485 | 0.88 | PDE7A (0.64) | PDE7ASMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2417324 | 0.88 | PDE7A (0.64) | PDE7ASMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8095611 | 0.88 | PDE7A (1.00) | PDE7ASMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1713219 | 0.87 | PDE7A (0.65) | PDE7ASMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30338244 | 0.87 | PDE7A (0.65) | PDE7ASMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL224666 | 0.86 | PDE7A (0.60) | PDE7ASMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22133428 | 0.85 | ALDH1A1 (0.65) | PDE7ASMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6930370 | 0.85 | PDE7A (0.59) | PDE7ASMN1; SMN2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2360372 | 0.84 | PDE7A (0.59) | PDE7ASMN1; SMN2SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697993-B | Pyrimidine compounds as AXL inhibitors | 南京正大天晴制药有限公司 | 2024-12-10 | — | — | CN | disclosed |