Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23355571 | 0.85 | KDM4E (0.38) | CYP4F2CYP4A11KDM4CKDM4EKDM6B | |
| SCHEMBL24323834 | 0.85 | KDM4E (0.38) | CYP4F2CYP4A11KDM4CKDM4EKDM6B | |
| SCHEMBL7373737 | 0.83 | KDM4E (0.38) | CYP4F2CYP4A11KDM4CKDM4EKDM6B | |
| SCHEMBL2350498 | 0.83 | ATR (0.35) | KDM4EALDH1A1ALOX15MAPTKMT2A | |
| SCHEMBL25659397 | 0.81 | SORD (0.41) | ALDH1A1ALOX15NPSR1 | |
| SCHEMBL25177349 | 0.79 | KMO (0.45) | KDM4EALDH1A1 | |
| SCHEMBL2762628 | 0.77 | KDM4E (0.40) | CYP4F2CYP4A11KDM4CKDM4EKDM6B | |
| SCHEMBL23355695 | 0.76 | BACE1 (0.36) | KDM4CKDM4EKDM6BKDM5CKDM2A | |
| SCHEMBL165741 | 0.75 | KDM4E (0.41) | KDM4CKDM4EKDM6BKDM5CKDM2A | |
| SCHEMBL7077382 | 0.75 | KMT2A (0.43) | KDM4CKDM4EKDM6BKDM5CKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867535-B | Substituted benzamides as modulators of TREX1 | 星座制药公司 | 2024-12-17 | — | — | CN | disclosed |