SCHEMBL31276286

SCHEMBL31276286

CN(C)/C=C/C(=O)c1ccccn1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.61
MAPT P10636 6/20 0.58
NPC1 O15118 3/20 0.58
RAB9A P51151 3/20 0.58
KDM4E B2RXH2 2/20 0.58
LMNA P02545 2/20 0.58
PKM P14618 2/20 0.58
ALDH1A1 P00352 3/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
HTT P42858 3/20 0.53
KMT2A Q03164 3/20 0.52
GAA P10253 2/20 0.52
MEN1 O00255 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
GPR52 Q9Y2T5 1/20 0.51
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
KRAS P01116 1/20 0.49
MITF O75030 1/20 0.49
TP53 P04637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1425 1.00 RECQL (0.61) RECQLMAPTNPC1RAB9AKDM4E
SCHEMBL15709976 1.00 RECQL (0.61) RECQLMAPTNPC1RAB9AKDM4E
SCHEMBL1424 1.00 RECQL (0.61) RECQLMAPTNPC1RAB9AKDM4E
SCHEMBL14354329 0.81 GPR52 (0.57) RECQLMAPTNPC1RAB9AKDM4E
SCHEMBL14354330 0.81 GPR52 (0.57) RECQLMAPTNPC1RAB9AKDM4E
SCHEMBL23251391 0.80 RECQL (0.61) RECQLMAPTNPC1RAB9ALMNA
SCHEMBL10950293 0.80 MAPT (0.64) MAPTNPC1RAB9AKDM4ELMNA
SCHEMBL10950289 0.80 MAPT (0.64) MAPTNPC1RAB9AKDM4ELMNA
SCHEMBL30208792 0.80 MAPT (0.64) MAPTNPC1RAB9AKDM4ELMNA
SCHEMBL30046046 0.80 RECQL (0.61) RECQLMAPTNPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025015429-A1 IMIDAZOPYRIMIDINE-BASED MULTIMETALLIC CATALYSTS SCHIPPER DEREK JAMES (CA) 2025-01-23 WO disclosed