Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31276196 | 0.96 | LMNA (0.56) | LMNANPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL31276891 | 0.91 | LMNA (0.51) | LMNANPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL31276191 | 0.88 | PTGS1 (0.66) | LMNANPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL31275605 | 0.88 | LMNA (0.49) | LMNANPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL31275608 | 0.88 | LMNA (0.58) | LMNANPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL31276119 | 0.88 | PTGS2 (0.50) | LMNANPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL31276345 | 0.85 | LMNA (0.46) | LMNANPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL31276318 | 0.85 | PTGS2 (0.52) | LMNANPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL31276291 | 0.85 | PTGS2 (0.66) | LMNANPSR1ALDH1A1NPC1RAB9A | |
| SCHEMBL31276340 | 0.84 | HIF1A (0.50) | LMNANPSR1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119019332-A | 1, 5-Disubstituted-4-bromopyrazole compound and preparation method and application thereof | 赣南师范大学 | 2024-11-26 | — | — | CN | disclosed |