Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.55 |
| ▸ | ESR1 | P03372 | 4/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.54 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 4/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.46 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1367873 | 1.00 | NOTUM (0.55) | NOTUMESR1ESR2ABHD6NAMPT | |
| SCHEMBL566389 | 0.87 | ESR1 (0.68) | NOTUMESR1ESR2ABHD6RIPK1 | |
| SCHEMBL30263783 | 0.87 | ESR1 (0.68) | NOTUMESR1ESR2ABHD6RIPK1 | |
| SCHEMBL26845990 | 0.86 | NOTUM (0.53) | NOTUMESR1ESR2ABHD6NAMPT | |
| SCHEMBL7786861 | 0.85 | ESR1 (0.53) | NOTUMESR1ESR2ABHD6NAMPT | |
| SCHEMBL5424954 | 0.84 | RIPK1 (0.72) | NOTUMESR1ESR2ABHD6RIPK1 | |
| SCHEMBL7524427 | 0.83 | ESR1 (0.44) | NOTUMESR1ESR2ABHD6NAMPT | |
| SCHEMBL25825897 | 0.81 | ABHD6 (0.47) | ESR1ESR2ABHD6HSP90AA1HSP90AB1 | |
| SCHEMBL506139 | 0.80 | ESR1 (0.59) | NOTUMESR1ESR2ABHD6RIPK1 | |
| SCHEMBL25604135 | 0.80 | ESR2 (0.77) | ESR1ESR2ABHD6HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4596534-A1 | NONCOVALENT SMALL-MOLECULE INHIBITORS OF THE KEAP1-NRF2 INTERACTION | University of Copenhagen (DK) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024259303-A1 | COMPOUNDS AND COMPOSITIONS AS CEREBLON LIGANDS AND USES THEREOF | ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) | 2024-12-19 | — | — | WO | disclosed |