Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25256747 | 1.00 | PIK3CA (0.51) | PIK3CAL3MBTL1MAPTPOLBMEN1 | |
| SCHEMBL25220780 | 0.83 | PIK3CA (0.47) | PIK3CAL3MBTL1MAPTPOLBMEN1 | |
| SCHEMBL30447441 | 0.83 | PIK3CA (0.47) | PIK3CAL3MBTL1MAPTPOLBMEN1 | |
| SCHEMBL25219873 | 0.78 | PIK3CA (0.47) | PIK3CAL3MBTL1POLBHTTHRH4 | |
| SCHEMBL30447687 | 0.78 | PIK3CA (0.47) | PIK3CAL3MBTL1POLBHTTHRH4 | |
| SCHEMBL25256261 | 0.77 | PIK3CA (0.47) | PIK3CAMAPTPOLBMEN1KMT2A | |
| SCHEMBL30448081 | 0.77 | PIK3CA (0.47) | PIK3CAMAPTPOLBMEN1KMT2A | |
| SCHEMBL11864650 | 0.75 | MAPT (0.52) | PIK3CAL3MBTL1MAPTMEN1KMT2A | |
| SCHEMBL4064654 | 0.75 | L3MBTL1 (0.52) | PIK3CAL3MBTL1MAPTPOLBMEN1 | |
| SCHEMBL25213865 | 0.74 | PIK3CA (0.48) | PIK3CAPOLBMEN1KMT2AHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118922188-A | Pyrimidine and methods of use thereof | 奇尼塔公司 | 2024-11-08 | — | — | CN | disclosed |