Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.57 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3699642 | 1.00 | KDM1A (0.57) | KDM1ACYP17A1CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL14824888 | 0.78 | SIGMAR1 (0.38) | KDM1AAKR1B1 | |
| SCHEMBL20449248 | 0.78 | BACE1 (0.48) | KDM1AAKR1B1PARP1PARP10 | |
| SCHEMBL24275641 | 0.78 | KDM1A (0.56) | KDM1ASLC6A4SLC6A3 | |
| SCHEMBL12188662 | 0.78 | KDM1A (0.56) | KDM1ACYP17A1CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL5722839 | 0.78 | CYP3A4 (0.37) | KDM1ACYP17A1CYP3A4CYP11B1CYP11B2 | |
| SCHEMBL6667048 | 0.75 | KDM1A (0.50) | KDM1ACYP3A4AKR1B1 | |
| SCHEMBL10157966 | 0.74 | NPC1 (0.37) | KDM1ANPC1RAB9A | |
| SCHEMBL10199817 | 0.74 | AKR1B1 (0.37) | KDM1ACYP3A4AKR1B1 | |
| SCHEMBL19398836 | 0.74 | KDM1A (0.36) | KDM1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720067-A1 | BICYCLIC HETEROARYLAMIDES HAVING GPR68 MODULATING ACTIVITY | Recursion Pharmaceuticals, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246559-A1 | BICYCLIC HETEROARYLAMIDES HAVING GPR68 MODULATING ACTIVITY | EXSCIENTIA AI LIMITED (GB) | 2024-12-05 | — | — | WO | disclosed |