Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 3/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1997077 | 1.00 | PIN1 (0.50) | PIN1HDAC9HCAR2ALDH1A1TP53 | |
| SCHEMBL4851505 | 0.89 | KDM1A (0.50) | PIN1HDAC9KDM1AAKR1C1 | |
| SCHEMBL15026087 | 0.85 | PIN1 (0.50) | PIN1HDAC9HCAR2ALDH1A1TP53 | |
| SCHEMBL14537318 | 0.85 | PIN1 (0.50) | PIN1HDAC9HCAR2ALDH1A1TP53 | |
| SCHEMBL2055553 | 0.84 | PIN1 (0.49) | PIN1HDAC9HCAR2ALDH1A1TP53 | |
| SCHEMBL3136514 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TDP1LMNAAKR1C1 | |
| SCHEMBL18736676 | 0.81 | HDAC9 (0.59) | PIN1HDAC9ALDH1A1TP53 | |
| SCHEMBL1471124 | 0.81 | PIN1 (0.53) | PIN1HDAC9HCAR2ALDH1A1TP53 | |
| SCHEMBL23715356 | 0.77 | KDM1A (0.45) | PIN1HDAC9ALDH1A1KDM1ATDP1 | |
| SCHEMBL19469462 | 0.77 | ALDH1A1 (0.43) | PIN1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4720067-A1 | BICYCLIC HETEROARYLAMIDES HAVING GPR68 MODULATING ACTIVITY | Recursion Pharmaceuticals, Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024246559-A1 | BICYCLIC HETEROARYLAMIDES HAVING GPR68 MODULATING ACTIVITY | EXSCIENTIA AI LIMITED (GB) | 2024-12-05 | — | — | WO | disclosed |