Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 7/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31278057 | 0.83 | HIF1A (0.57) | PLK1LMNAPKMALOX15ALDH1A1 | |
| Hydrochloric Acid SCHEMBL31278432 | 0.81 | TSHR (0.52) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL31277333 | 0.80 | MAPT (0.50) | LMNAPKMALOX15ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL31278071 | 0.78 | GRM4 (0.55) | LMNANPSR1ALDH1A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL31277879 | 0.74 | MEN1 (0.51) | LMNAPKMALOX15ALDH1A1MAPT | |
| SCHEMBL12136748 | 0.74 | RAB9A (0.59) | PLK1NPSR1ALDH1A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL31277222 | 0.74 | KMT2A (0.56) | LMNAPKMNPSR1ALOX15ALDH1A1 | |
| SCHEMBL31277648 | 0.74 | ALDH1A1 (0.63) | LMNAPKMALOX15ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL31277305 | 0.72 | ALDH1A1 (0.57) | LMNAPKMALOX15ALDH1A1MAPT | |
| SCHEMBL31277744 | 0.72 | ALDH1A1 (0.57) | LMNAPKMALOX15ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024246946-A1 | NOVEL PYRIDINE CARBOXAMIDE COMPOUNDS WITH ANTI-TUBERCULAR ACTIVITY | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2024-12-05 | — | — | WO | claimed |
| WO-2024246946-A1 | NOVEL PYRIDINE CARBOXAMIDE COMPOUNDS WITH ANTI-TUBERCULAR ACTIVITY | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2024-12-05 | — | — | WO | disclosed |