Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | CTSE | P14091 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 2/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.32 |
| ▸ | CDK9 | P50750 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32664703 | 1.00 | BACE1 (0.36) | BACE1CTSDCTSESLC2A1HRH1 | |
| SCHEMBL31279004 | 0.92 | SLC2A1 (0.35) | BACE1CTSDCTSESLC2A1HRH1 | |
| SCHEMBL32664570 | 0.92 | SLC2A1 (0.35) | BACE1CTSDCTSESLC2A1HRH1 | |
| SCHEMBL29737046 | 0.86 | SLC2A1 (0.36) | BACE1CTSDCTSESLC2A1HRH1 | |
| SCHEMBL18289976 | 0.86 | HTR6 (0.40) | BACE1CTSDCTSESLC2A1HRH1 | |
| SCHEMBL30111801 | 0.86 | HTR6 (0.40) | BACE1CTSDCTSESLC2A1HRH1 | |
| SCHEMBL32664297 | 0.85 | SLC2A1 (0.35) | BACE1CTSDCTSESLC2A1HRH1 | |
| SCHEMBL31280171 | 0.85 | SLC2A1 (0.35) | BACE1CTSDCTSESLC2A1HRH1 | |
| SCHEMBL31278495 | 0.82 | BTK (0.46) | BTK | |
| SCHEMBL32664459 | 0.82 | BTK (0.46) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119343340-A | Methods of preparing modified BTK inhibitors | 普林斯匹亚生物制药公司 | 2025-01-21 | — | — | CN | disclosed |