Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | CTSE | P14091 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | MERTK | Q12866 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31280171 | 0.92 | SLC2A1 (0.35) | SLC2A1BACE1GPR119OPRM1CTSD | |
| SCHEMBL32664297 | 0.92 | SLC2A1 (0.35) | SLC2A1BACE1GPR119OPRM1CTSD | |
| SCHEMBL30111801 | 0.88 | HTR6 (0.40) | SLC2A1BACE1OPRM1CTSDCTSE | |
| SCHEMBL18289976 | 0.88 | HTR6 (0.40) | SLC2A1BACE1OPRM1CTSDCTSE | |
| SCHEMBL32664570 | 0.87 | SLC2A1 (0.35) | SLC2A1BACE1GPR119OPRM1CTSD | |
| SCHEMBL31279004 | 0.87 | SLC2A1 (0.35) | SLC2A1BACE1GPR119OPRM1CTSD | |
| SCHEMBL32664703 | 0.86 | BACE1 (0.36) | SLC2A1BACE1OPRM1CTSDCTSE | |
| SCHEMBL31279119 | 0.86 | BACE1 (0.36) | SLC2A1BACE1OPRM1CTSDCTSE | |
| SCHEMBL22902468 | 0.83 | L3MBTL1 (0.39) | OPRM1HRH1HRH4CDK5CDK5R1 | |
| SCHEMBL22902459 | 0.82 | OPRM1 (0.35) | OPRM1HRH1HRH4ALDH1A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12624030-B2 | 4-amino-3-(4-phenoxyphenyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one derivatives and salts thereof | PRINCIPIA BIOPHARMA INC. (US) | 2026-05-12 | — | — | US | disclosed |
| US-20240051955-A1 | 4-AMINO-3-(4-PHENOXYPHENYL)-1,3-DIHYDRO-2H-IMIDAZO[4,5-C]PYRIDIN-2-ONE DERIVATIVES AND SALTS THEREOF | GENZYME CORPORATION (US) | 2024-02-15 | — | — | US | disclosed |
| EP-4267572-A1 | 4-AMINO-3-(4-PHENOXYPHENYL)-1,3- DIHYDRO-2H-IMIDAZO[4,5-C]PYRIDIN-2-ONE DERIVATIVES AND SALTS THEREOF | GENZYME CORPORATION (US) | 2023-11-01 | — | — | EP | disclosed |
| WO-2022140511-A1 | 4-AMINO-3-(4-PHENOXYPHENYL)-1,3- DIHYDRO-2H-IMIDAZO[4,5-C]PYRIDIN-2-ONE DERIVATIVES AND SALTS THEREOF | GENZYME CORPORATION (US) | 2022-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240051955-A1 | 4-AMINO-3-(4-PHENOXYPHENYL)-1,3-DIHYDRO-2H-IMIDAZO[4,5-C]PYRIDIN-2-ONE DERIVATIVES AND SALTS THEREOF | ADRA2C, P2RY4, HTR2C | SLC2A1 2463/4885BACE1 3583/4885GPR119 295/4885 |
| US-12624030-B2 | 4-amino-3-(4-phenoxyphenyl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one derivatives and salts thereof | ADRA1D, ADRA2C, P2RY1 | SLC2A1 744/4885BACE1 2058/4885GPR119 1203/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.