Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 11/20 | 0.48 |
| ▸ | DDB1 | Q16531 | 9/20 | 0.48 |
| ▸ | IKZF3 | Q9UKT9 | 7/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31278850 | 0.92 | ADRA1D (0.42) | PARP1KCNH2ADRA1BADRA1DADRA1A | |
| SCHEMBL31278930 | 0.87 | DRD4 (0.48) | PARP1ADRA1BADRA1DADRA1ACRBN | |
| SCHEMBL31279578 | 0.86 | KDM4E (0.41) | PARP1KCNH2ADRA1BADRA1DADRA1A | |
| SCHEMBL31279521 | 0.85 | DRD2 (0.46) | ADRA1BADRA1DADRA1ACRBNDDB1 | |
| SCHEMBL31279758 | 0.85 | DRD4 (0.39) | PARP1ADRA1BADRA1DADRA1ACRBN | |
| SCHEMBL31279517 | 0.85 | CRBN (0.48) | PARP1KCNH2ADRA1BADRA1DADRA1A | |
| SCHEMBL31279378 | 0.84 | CRBN (0.48) | CRBNDDB1IKZF3DRD2HTR7 | |
| SCHEMBL31279375 | 0.84 | CRBN (0.46) | PARP1ADRA1BADRA1DADRA1ACRBN | |
| SCHEMBL31279863 | 0.83 | DRD2 (0.41) | PARP1ADRA1BADRA1DADRA1ACRBN | |
| SCHEMBL31279117 | 0.83 | CRBN (0.47) | PARP1ADRA1BADRA1DADRA1ACRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4722207-A1 | OXOISOINDOLINYL-SUBSTITUTED TETRAHYDROPYRIMIDINEDIONE DERIVATIVE AND USE THEREOF | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-04-08 | — | — | EP | claimed |
| CN-119451952-A | Oxo-isoindolinyl substituted tetrahydropyrimidinedione derivative and application thereof | 标新生物医药科技(上海)有限公司 | 2025-02-14 | — | — | CN | claimed |
| WO-2024245444-A1 | OXOISOINDOLINYL-SUBSTITUTED TETRAHYDROPYRIMIDINEDIONE DERIVATIVE AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-12-05 | — | — | WO | claimed |
| EP-4722207-A1 | OXOISOINDOLINYL-SUBSTITUTED TETRAHYDROPYRIMIDINEDIONE DERIVATIVE AND USE THEREOF | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-04-08 | — | — | EP | disclosed |
| CN-119451952-A | Oxo-isoindolinyl substituted tetrahydropyrimidinedione derivative and application thereof | 标新生物医药科技(上海)有限公司 | 2025-02-14 | — | — | CN | disclosed |
| WO-2024245444-A1 | OXOISOINDOLINYL-SUBSTITUTED TETRAHYDROPYRIMIDINEDIONE DERIVATIVE AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-12-05 | — | — | WO | disclosed |