Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 17/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR1F | P30939 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14321207 | 1.00 | HTR6 (0.42) | HTR6DRD2HTR2AMETCYP2C19 | |
| SCHEMBL2128761 | 0.87 | ABL1 (0.45) | HTR6ALDH1A1HTTABL1BCR | |
| SCHEMBL16916911 | 0.84 | PIK3C3 (0.48) | HTR6DRD2HTR2AMETCYP2C19 | |
| SCHEMBL2369536 | 0.84 | HTR6 (0.51) | HTR6DRD2HTR2AMETCYP2C19 | |
| SCHEMBL16923796 | 0.81 | HTR6 (0.48) | HTR6DRD2HTR2AMETCYP2C19 | |
| SCHEMBL19278216 | 0.80 | ABL1 (0.36) | HTR6ALDH1A1LMNAHTTABL1 | |
| SCHEMBL23462051 | 0.79 | HTR6 (0.47) | HTR6DRD2HTR2AMETCYP2C19 | |
| SCHEMBL3723254 | 0.78 | CYP2C19 (0.48) | HTR6DRD2HTR2AMETCYP2C19 | |
| SCHEMBL26912429 | 0.77 | HTR6 (0.43) | HTR6DRD2HTR2AMEN1ALDH1A1 | |
| SCHEMBL2216316 | 0.76 | HTR6 (0.51) | HTR6DRD2HTR2AMETMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119161324-A | Methods and compounds for restoring mutant p53 function | 皮姆维制药公司 | 2024-12-20 | — | — | CN | disclosed |